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How to Make Homemade Neosporin

As my oldest daughter grows older, she has become an accident waiting to happen. (She takes after her clumsy aunt.) She’s always had a rough side to her, and she’s so curious and exploratory that it’s not abnormal for her to get hurt or come to me with a new injury to document her conquests.

We’re a big band-aid family, often exploring the different styles and patterns in the medicine isle. But instead of also splurging on Neosporin to use to aid the healing process, I have discovered an easy way to make an all-natural alternative. All of the ingredients in the recipe below work together to create a really powerful healing salve similar to the healing properties of over the counter Neosporin creme. It is also great for diaper rash and dry skin issues.

homemade neosporin 2

Natural Homemade Neosporin

mrh1/2 cup coconut oil
1/2 cup extra virgin olive oil
1/4 cup dried comfrey
1/4 cup dried calendula
2oz beeswax (equals out to 2 of the 1oz bars or 4 tablespoons)
2 tablespoons of honey (optional)
10 drops lavender essential oil (optional)

There are two ways to do this. They both yield similar results, but the first method is said to have more of a herbal kick. If you want to put an emphasis on the herbal healing power, use method one. Otherwise, the short cut method listed second is suitable for this recipe.

Method 1:

Measure the comfry, calendula, and olive oil. Mix together and place in a glass jar with a lid. Leave the jar in a safe spot for 4-6 weeks. After the herbs have been infused, use cheesecloth or coffee filter to strain the oil. Add the herb-infused olive oil and coconut oil in a medium saucepan and warm on low heat for a few minutes until you reach a well blended smooth consistency.

homemade neosporin filter

Continue with Step 2.

Method 2 (short-cut method):

In a medium saucepan combine the coconut oil, olive oil, comfrey, & calendula. Cook on medium-low heat for about 20-30 minutes, stirring often. Be particularly careful not to burn your oil. You don’t want to deep fry the herbs. Keep a close eye on it and remove from heat at the first sign of overcooking. The oil should be green, not black (see above photo).

homemade neosporin short cut method

Strain the oils using a cheesecloth or coffee filter. Toss the herbs. Wipe out any remaining herbs from your saucepan and add the strained oil back to your pot. Turn the heat to low.

Step 2:

If you’re adding honey, now is the time. Having the honey mix in evenly can be somewhat tedious, so you can opt to omit it if you wish. However, honey is a natural moisturizer with awesome anti-microbial properties. Add the honey slowly and mix thoroughly. If the honey won’t mix in the temperature of the mix could be too low. If the honey doesn’t mix in it will settle to the top and can be drained off later.

Whether you’re adding honey or not, the next step is to add the beeswax. If you’re using bars, cut into slices or grate with a cheese grater before adding. This will allow for  quicker melting times.

homemade neosporin MIRA scale

Because I buy my beeswax in bulk, I have to cut it up and slice it for all of my homemade salves and balms. I then bust out my MIRA digital kitchen scale for accuracy. This baby has beautiful tempered glass and can measure up to 11 pounds, so two ounces is no big deal.

Once the beeswax is properly measured add the 2 ounces to the herbal oil. Stir the mixture until the beeswax is completely melted.

At this point stir in the lavender essential oil if you decide to use it. Once combined, remove the mixture from the heat.

Step 3:

You’ll want to work quickly now as the salve starts to set up rather fast. Pour into the glass container(s) or tin(s) of your choice. You can even try your hand at push up containers. (I’ve never been successful with them.) I save containers all the time, so I just used what I had on hand.

homemade neosporin

Each batch makes 16 ounces. It keeps for a year.


Disclaimer: I received one or more of the products mentioned above for free using Regardless, I only recommend products or services I use personally and believe will be good for my readers. This post also includes affiliate links. I shall not tell lies!





  1. Awesome idea! I just need to figure out where I can buy all those herbs. And where did you get that scale? I love it! (Yes, I’m weird.)

  2. I NEEDED this! I’m always trying to find the stinkin’ tube of Neosporin when Sophia gets a cut or scrape and always remember I forgot to buy it. I’d love to make it myself. I’m a little concerned that I may not be able to find all the ingredients though? I need to get to looking!

    • I have a great local natural foods store that carries bulk herbs. Frontier also offers great wholesale prices for every ingredient in this tutorial. And of course, everything is on Amazon. 🙂

  3. I have been meaning to make something like this for a while. Thanks for sharing. Pinning the recipe!

  4. Thank you for this step-by-step recipe! I love experimenting with making my own products at home, especially when I know there are only the safest ingredients. Can’t wait to try this one.

  5. sarah ann says:

    This recipe is genius! I never thought about making an ointment, but I’ll definitely be giving this easy recipe a try!

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